This syndrome, also known as central pain syndrome, is caused by a lacunar stroke in an area of the brain called the thalamus. This area serves as the relay station for sensory information from all over the body. The stroke is specific to areas of the thalamus that receive information about pain, temperature, touch, vibration sense, and pressure from all over the body. Lacunar strokes to these areas are usually caused by an blockage in a small branch of an artery in the brain which normally carries blood to them.
Symptoms of Dejerine-Roussy Syndrome
The symptoms of the Dejerine-Roussy syndrome include the following:- Unexplained pain coming from one side of the body
- Abnormal sensation of pain to a normal stimulus, such as a gentle stroke over the skin
- Tingling feelings from one side of the body
- Feelings of excessive weight on one side of the body
- Abnormal feelings of hot or cold on one side of the body
Sometimes the syndrome is accompanied by weakness on the face, arm, and/or leg on one side of the body, which begins shortly after the stroke. This weakness normally goes away over time, but the rest of the symptoms can be permanent.
The sensory symptoms of the Dejerine-Roussy syndrome can begin immediately after the stroke, or come on slowly over the subsequent weeks, or months.
Treatment of Dejerine-Roussy Syndrome
Available treatments for the Dejerine-Roussy syndrome include antidepressants, anticonvulsants and analgesic medications. In severe cases, people are given strong pain medicines such as morphine and methadone. Surgical options also exist; deep brain stimulation is used to decrease a person's perception of pain.
For more information about the treatments of Dejerine-Roussy syndrome, visit the Central Pain Syndrome Alliance website.
Source: J. P. Mohr, Dennis W. Choi, James C. Grotta, Bryce Weir, Phillip A. Wolf Stroke: Pathophysiology, Diagnosis, and Management Churchill Livingstone; 4th edition (2004)
