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Lupus Anticoagulant

From Jose Vega M.D., Ph.D., for About.com

Updated: September 17, 2008

About.com Health's Disease and Condition content is reviewed by the Medical Review Board

Lupus anticoagulants can be found on a blood testPhoto © A.D.A.M.
Definition: The presence of one or more antibodies in the blood which attack the body's own cells by binding to their membrane phospholids. This abnormal binding sets off a cascade of molecular events that leads to a state that favors blood clot formation, and in some cases it can lead to embolic strokes.
Also Known As: antiphospholipid antibodies
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